Pharmacokinetics of Recombinant Human Tumor Necrosis Factor Alpha in the Delivery System

Pharmacokinetics of Recombinant Human Tumor Necrosis Factor Alpha in the Delivery System

The main problems of using TNF-alpha in antitumor therapy are its rapid degradation in the bloodstream and the limited selectivity of accumulation in the tumor tissue. The SRC VB «Vector» developed a biodegradable molecular construct that provides protection against proteases and ensures targeted de...

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Bibliographic Details
Main Authors:	A. V. Bateneva, O. V. Simakova, S. G. Gamaley, E. A. Volosnikova, L. R. Lebedev, E. D. Danilenko
Format:	Article
Language:	Russian
Published:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2019-09-01
Series:	Биопрепараты: Профилактика, диагностика, лечение
Subjects:	pharmacokinetics tumor necrosis factor alpha molecular construct outbred mice delivery system
Online Access:	https://www.biopreparations.ru/jour/article/view/232

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