Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing

In label-free biosensing surface functionalisation is a complex issue that can affect sensing performance. Here, the authors report on an electrostatic layer-by-layer technique to functionalize a surface and demonstrate this technique using biotinylated polymer for streptavidin detection in saliva.

Bibliographic Details
Main Authors:	Stefano Mariani, Valentina Robbiano, Lucanos M. Strambini, Aline Debrassi, Gabriela Egri, Lars Dähne, Giuseppe Barillaro
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-12-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-07723-8

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spelling	doaj-3ce1e64ca68a4c3ca778db24344f2c7b2021-05-11T09:36:37ZengNature Publishing GroupNature Communications2041-17232018-12-019111310.1038/s41467-018-07723-8Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensingStefano Mariani0Valentina Robbiano1Lucanos M. Strambini2Aline Debrassi3Gabriela Egri4Lars Dähne5Giuseppe Barillaro6Dipartimento di Ingegneria dell’Informazione, Università di PisaDipartimento di Ingegneria dell’Informazione, Università di PisaIstituto di Elettronica e di Ingegneria dell’Informazione e delle Telecomunicazioni, Consiglio Nazionale delle RicercheSurflay Nanotec GmbHSurflay Nanotec GmbHSurflay Nanotec GmbHDipartimento di Ingegneria dell’Informazione, Università di PisaIn label-free biosensing surface functionalisation is a complex issue that can affect sensing performance. Here, the authors report on an electrostatic layer-by-layer technique to functionalize a surface and demonstrate this technique using biotinylated polymer for streptavidin detection in saliva.https://doi.org/10.1038/s41467-018-07723-8
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Stefano Mariani Valentina Robbiano Lucanos M. Strambini Aline Debrassi Gabriela Egri Lars Dähne Giuseppe Barillaro
spellingShingle	Stefano Mariani Valentina Robbiano Lucanos M. Strambini Aline Debrassi Gabriela Egri Lars Dähne Giuseppe Barillaro Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing Nature Communications
author_facet	Stefano Mariani Valentina Robbiano Lucanos M. Strambini Aline Debrassi Gabriela Egri Lars Dähne Giuseppe Barillaro
author_sort	Stefano Mariani
title	Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
title_short	Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
title_full	Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
title_fullStr	Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
title_full_unstemmed	Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
title_sort	layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-12-01
description	In label-free biosensing surface functionalisation is a complex issue that can affect sensing performance. Here, the authors report on an electrostatic layer-by-layer technique to functionalize a surface and demonstrate this technique using biotinylated polymer for streptavidin detection in saliva.
url	https://doi.org/10.1038/s41467-018-07723-8
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Layer-by-layer biofunctionalization of nanostructured porous silicon for high-sensitivity and high-selectivity label-free affinity biosensing

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