Mesenchymal stem cells as a double-edged sword in tumor growth: focusing on MSC-derived cytokines

Mesenchymal stem cells as a double-edged sword in tumor growth: focusing on MSC-derived cytokines

Abstract Mesenchymal stem cells (MSCs) show homing capacity towards tumor sites. Numerous reports indicate that they are involved in multiple tumor-promoting processes through several mechanisms, including immunosuppression; stimulation of angiogenesis; transition to cancer-associated fibroblasts; i...

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Bibliographic Details
Main Authors: Wenqing Liang, Xiaozhen Chen, Songou Zhang, Jian Fang, Meikai Chen, Yifan Xu, Xuerong Chen
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Cellular & Molecular Biology Letters
Subjects:
Angiogenesis
Cancer-associated fibroblasts
Immunosuppression
Metastasis
Mesenchymal stem cells
Online Access:https://doi.org/10.1186/s11658-020-00246-5

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