Phospholipase A2 relieves phosphatidylcholine inhibition of micellar cholesterol absorption and transport by human intestinal cell line Caco-21

Phospholipase A2 relieves phosphatidylcholine inhibition of micellar cholesterol absorption and transport by human intestinal cell line Caco-21

Cholesterol absorption from bile acid micelles is suppressed by phosphatidylcholine (PC) in the micelles. The effects of micellar phospholipid composition on absorption, metabolism, and secretion of lipids were examined in Caco-2 cells incubated with micelles composed of taurocholic acid, cholestero...

Full description

Bibliographic Details
Main Authors:	Reynold Homan, Katherine L. Hamelehle
Format:	Article
Language:	English
Published:	Elsevier 1998-06-01
Series:	Journal of Lipid Research
Subjects:	enterocyte micelle bile acid phospholipid monoacylglycerol triacylglycerol
Online Access:	http://www.sciencedirect.com/science/article/pii/S002222752032544X

Similar Items

Scavenger receptor class B type I reduces cholesterol absorption in cultured enterocyte CaCo-2 cells1
by: Lei Cai, et al.
Published: (2004-02-01)

A Shift in Glycerolipid Metabolism Defines the Follicular Fluid of IVF Patients with Unexplained Infertility
by: Albert Batushansky, et al.
Published: (2020-07-01)

From lipid secretion to cholesterol crystallization in bile. Relevance in cholesterol gallstone disease
by: Piero Portincasa, MD, PhD, et al.
Published: (2002-07-01)

New Concepts of Mechanisms of Intestinal Cholesterol Absorption
by: David Q.H. Wang, MD, PhD
Published: (2003-07-01)

Comparison of α-Tocopherol, α-Tocopherol Acetate, and α-Tocopheryl Polyethylene Glycol Succinate 1000 Absorption by Caco-2 TC7 Intestinal Cells
by: Charlotte Cuerq, et al.
Published: (2021-12-01)

Effects of intestinal fatty acid-binding protein overexpression on fatty acid metabolism in Caco-2 cells
by: Christian Darimont, et al.
Published: (2000-01-01)

Characterization of model bile using fluorescence energy transfer from dehydroergosterol to dansylated lecithin
by: Steven P. Wrenn, et al.
Published: (2001-06-01)

Lipase-catalyzed glycerolysis extended to the conversion of a variety of edible oils into structural fats
by: Reed A. Nicholson, et al.
Published: (2021-01-01)

Asymmetric distribution of phosphatidylcholine and sphingomyelin between micellar and vesicular phases: potential implications for canalicular bile formation1
by: Erik R.M. Eckhardt, et al.
Published: (1999-11-01)

Delineation of molecular changes in intrahepatic cholesterol metabolism resulting from diminished cholesterol absorption
by: Joyce J. Repa, et al.
Published: (2005-04-01)

MGAT2 deficiency ameliorates high-fat diet-induced obesity and insulin resistance by inhibiting intestinal fat absorption in mice
by: Tsuchida Takuma, et al.
Published: (2012-06-01)

Intestinal de novo phosphatidylcholine synthesis is required for dietary lipid absorption and metabolic homeostasis
by: John P. Kennelly, et al.
Published: (2018-09-01)

Baculovirus-mediated expression of recombinant rat phosphatidylcholine transfer protein
by: Li Feng, et al.
Published: (1998-09-01)

Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity
by: John D. Douglass, et al.
Published: (2015-06-01)

Impaired response of biliary lipid secretion to a lithogenic diet in phosphatidylcholine transfer protein-deficient mice
by: Michele K. Wu, et al.
Published: (2005-03-01)

Genetic factors at the enterocyte level account for variations inintestinal cholesterol absorption efficiency among inbred strains of mice1
by: David Q-H. Wang, et al.
Published: (2001-11-01)

Dietary Phospholipids and Intestinal Cholesterol Absorption
by: Sally Tandy, et al.
Published: (2010-02-01)

Mise au point sur l’analyse de la régiodistribution en acides gras des triacylglycérols
by: Turon Fabrice
Published: (2003-03-01)

Differing rates of cholesterol absorption among inbred mouse strains yield differing levels of HDL-cholesterol
by: Timothy J. Sontag, et al.
Published: (2013-09-01)

Comparison of bile salt/phosphatidylcholine mixed micelles in solubilization to sterols and stability
by: Guo Q, et al.
Published: (2016-11-01)

Partition of lipids between emulsified oil and micellar phases of glyceride-bile salt dispersions
by: Bengt Borgström
Published: (1967-11-01)

Phospholipid-Conjugated PEG-<i>b</i>-PCL Copolymers as Precursors of Micellar Vehicles for Amphotericin B
by: Elsa R. Arias, et al.
Published: (2021-05-01)

Deficiency of MGAT2 increases energy expenditure without high-fat feeding and protects genetically obese mice from excessive weight gain
by: David W. Nelson, et al.
Published: (2011-09-01)

Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats[S]
by: Gudrun Schober, et al.
Published: (2013-05-01)

Metabolism of apical versus basolateral sn-2-monoacylglycerol and fatty acids in rodent small intestine*
by: Judith Storch, et al.
Published: (2008-08-01)

A study on the inhibitory mechanism for cholesterol absorption by α-cyclodextrin administration
by: Takahiro Furune, et al.
Published: (2014-12-01)

Kinetic dependence of phospholipase A2 activity on the detergent Triton X-100
by: Edward A. Dennis
Published: (1973-03-01)

Transport of vitamin E by differentiated Caco-2 cells
by: Kamran Anwar, et al.
Published: (2006-06-01)

Thyroid hormone receptor β1 stimulates ABCB4 to increase biliary phosphatidylcholine excretion in mice
by: Julien Gautherot, et al.
Published: (2018-09-01)

Siamese neem flower extract suppresses cholesterol absorption by interfering NPC1L1 and micellar property in vitro and in intestinal Caco-2 cells
by: Acharaporn Duangjai, et al.
Published: (2019-01-01)

Lipolysis and lipases in white adipose tissue – An update
by: Andressa Bolsoni-Lopes, et al.

Expression of mouse MGAT in Arabidopsis results in increased lipid accumulation in seeds
by: Anna eEl Tahchy, et al.
Published: (2015-12-01)

Fluorescence spectroscopy measures yeast PAH1-encoded phosphatidate phosphatase interaction with liposome membranes
by: Zhi Xu, et al.
Published: (2012-03-01)

Spirogyra neglecta inhibits the absorption and synthesis of cholesterol in vitro
by: Acharaporn Duangjai, et al.
Published: (2016-12-01)

Adult-onset deficiency of acyl CoA:monoacylglycerol acyltransferase 2 protects mice from diet-induced obesity and glucose intolerance[S]
by: Taylor Banh, et al.
Published: (2015-02-01)

Détection luminale des micelles lipidiques
by: Beaslas Olivier, et al.
Published: (2012-07-01)

Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport
by: Tomomi Hashidate-Yoshida, et al.
Published: (2015-04-01)

GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis[S]
by: Dandan Shan, et al.
Published: (2010-07-01)

Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects[S]
by: Cédric M. Blouin, et al.
Published: (2010-05-01)

Quantitation of cholesterol crystallization from supersaturated model bile1
by: Piero Portincasa, et al.
Published: (2002-04-01)