Sodium iodate induces ferroptosis in human retinal pigment epithelium ARPE-19 cells

Abstract Sodium iodate (SI) is a widely used oxidant for generating retinal degeneration models by inducing the death of retinal pigment epithelium (RPE) cells. However, the mechanism of RPE cell death induced by SI remains unclear. In this study, we investigated the necrotic features of cultured hu...

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Bibliographic Details
Main Authors: Binghua Liu, Weiyan Wang, Arman Shah, Meng Yu, Yang Liu, Libo He, Jinye Dang, Li Yang, Mengli Yan, Yuling Ying, Zihuai Tang, Ke Liu
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03520-2