Fatp1 deficiency affects retinal light response and dark adaptation, and induces age-related alterations.

FATP1 is involved in lipid transport into cells and in intracellular lipid metabolism. We showed previously that this protein interacts with and inhibits the limiting-step isomerase of the visual cycle RPE65. Here, we aimed to analyze the effect of Fatp1-deficiency in vivo on the visual cycle, struc...

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Bibliographic Details
Main Authors: Karim Chekroud, Laurent Guillou, Stephane Grégoire, Gilles Ducharme, Emilie Brun, Chantal Cazevieille, Lionel Bretillon, Christian P Hamel, Philippe Brabet, Marie O Pequignot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3500375?pdf=render