TOSO interacts with SYK and enhances BCR pathway activation in chronic lymphocytic leukemia

Abstract. Background. TOSO, also named Fas inhibitory molecule 3 (FAIM3), has recently been identified as an immunoglobulin M (IgM) Fc receptor (FcμR). Previous studies have shown that TOSO is specifically over-expressed in chronic lymphocytic leukemia (CLL). However, the functions of TOSO in CLL re...

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Bibliographic Details
Main Authors: Yan-Ru Zhang, Zhen Yu, Wen-Jie Xiong, Xu-Xiang Liu, Hui-Min Liu, Rui Cui, Qi Wang, Wen-Ming Chen, Lu-Gui Qiu, Shu-Hua Yi, Peng Lyu.
Format: Article
Language:English
Published: Wolters Kluwer 2020-09-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000999