Zfp238 Regulates the Thermogenic Program in Cooperation with Foxo1

Summary: Obesity has become an explicit public health concern because of its relevance to metabolic syndrome. Evidence points to the significance of beige adipocytes in regulating energy expenditure. Here, using yeast two-hybrid screening, we show that Zfp238 is a Foxo1 co-repressor and that adipose...

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Bibliographic Details
Main Authors: Motoko Kita, Jun Nakae, Yoshinaga Kawano, Hiroshi Asahara, Hiroshi Takemori, Haruo Okado, Hiroshi Itoh
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219300057