Toll-Like Receptor 4 in the Rat Caudal Medulla Mediates Tooth Pulp Inflammatory Pain

Toll-Like Receptor 4 in the Rat Caudal Medulla Mediates Tooth Pulp Inflammatory Pain

The aims of this study were to investigate if Toll-like receptor 4 (TLR4) is expressed in the medullary dorsal horn (MDH) and if medullary application of a TLR4 antagonist (lipopolysaccharides from Rhodobacter sphaeroides, LPS-RS) can attenuate changes in nociceptive sensorimotor responses or TLR4 e...

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Bibliographic Details
Main Authors: Helena F. Filippini, Graziella R. Molska, Maryam Zanjir, Yamini Arudchelvan, Siew-Ging Gong, Maria M. Campos, Limor Avivi-Arber, Barry J. Sessle
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neuroscience
Subjects:
mustard oil
tooth pulp inflammation
toll-like receptor – 4
electromyography
LPS
LPS-RS
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00643/full

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