Oral Biofilms: Development, Control, and Analysis

The oral cavity harbors hundreds of microbial species that are present either as planktonic cells or incorporated into biofilms. The majority of the oral microbes are commensal organisms. Those that are pathogenic microbes can result in oral infections, and at times can initiate systemic diseases. B...

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Bibliographic Details
Main Authors: Daniela Berger, Aviva Rakhamimova, Andrew Pollack, Zvi Loewy
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:High-Throughput
Subjects:
Online Access:http://www.mdpi.com/2571-5135/7/3/24
Description
Summary:The oral cavity harbors hundreds of microbial species that are present either as planktonic cells or incorporated into biofilms. The majority of the oral microbes are commensal organisms. Those that are pathogenic microbes can result in oral infections, and at times can initiate systemic diseases. Biofilms that contain pathogens are challenging to control. Many conventional antimicrobials have proven to be ineffective. Recent advances in science and technology are providing new approaches for pathogen control and containment and methods to characterize biofilms. This perspective provides (1) a general understanding of biofilm development; (2) a description of emerging chemical and biological methods to control oral biofilms; and (3) an overview of high-throughput analytical approaches to analyze biofilms.
ISSN:2571-5135