No Effect of Dose Adjustment to the CYP2D6 Genotype in Patients With Severe Mental Illness

No Effect of Dose Adjustment to the CYP2D6 Genotype in Patients With Severe Mental Illness

Background: The CYP2D6 enzyme is involved in the metabolism of numerous psychopharmacological drugs. Guidelines recommend how to adjust the dose of medication based on the CYP2D6 genotype.Aims: To evaluate the effect of dose adjustment to the CYP2D6 genotype and phenotype, in patients with severe me...

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Bibliographic Details
Main Authors: Anne B. Koopmans, David J. Vinkers, Igmar T. Poulina, Petra J. A. Gelan, Ron H. N. van Schaik, Hans W. Hoek, Peter N. van Harten
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Psychiatry
Subjects:
CYP2D6
severe mental illness (SMI)
guidelines
dose adjustment
genotyping
psychopharmacology
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00349/full

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https://www.frontiersin.org/article/10.3389/fpsyt.2018.00349/full

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