Comparative analysis of chromogenic vs clot based cdc modified, nijmegen-bethesda assay for detection of factor VIII inhibitor titre

Comparative analysis of chromogenic vs clot based cdc modified, nijmegen-bethesda assay for detection of factor VIII inhibitor titre

Background:- Inhibitors to infused factor VIII are the most significant complication of hemophilia treatment. These inhibitors are usually IgG antibodies, that react with FVIII in a time and temperature dependent manner. Coagulation factor VIII inhibitors can be detected by Chromogenic, clot based a...

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Bibliographic Details
Main Authors: Mirza Asif Baig, Mohammad Shahid Iqbal, Abdel Rahim Mahmoud Muddathir, Aisha Tabassum, M Syeda Sarah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Nigerian Journal of Medicine
Subjects:
hemophilia
bethesda assay
elisa
factor viii
inhibitor
mixing studyabbrevations: apla- antiphospholipid antibody syndrome
cdc:nba- centers for disease control and prevention - nijmegen-bethesda assay
cnba:- chromogenic nijmegen bethesda assaynpp- normal pooled plasma
lac – lupus anticoagulant
Online Access:http://www.njmonline.org/article.asp?issn=1115-2613;year=2019;volume=28;issue=4;spage=423;epage=430;aulast=Baig;type=0

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http://www.njmonline.org/article.asp?issn=1115-2613;year=2019;volume=28;issue=4;spage=423;epage=430;aulast=Baig;type=0

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