Is aggregated synthetic amorphous silica toxicologically relevant?

Is aggregated synthetic amorphous silica toxicologically relevant?

Abstract Background The regulatory definition(s) of nanomaterials (NMs) frequently uses the term ‘agglomerates and aggregates’ (AA) despite the paucity of evidence that AA are significantly relevant from a nanotoxicological perspective. This knowledge gap greatly affects the safety assessment and re...

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Bibliographic Details
Main Authors: Sivakumar Murugadoss, Sybille van den Brule, Frederic Brassinne, Noham Sebaihi, Jorge Mejia, Stéphane Lucas, Jasmine Petry, Lode Godderis, Jan Mast, Dominique Lison, Peter H. Hoet
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Particle and Fibre Toxicology
Subjects:
Nanomaterials
Synthetic amorphous silica
Aggregates
In vitro toxicity
Biological activity
Online Access:https://doi.org/10.1186/s12989-019-0331-3

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