Target motifs affecting natural immunity by a constitutive CRISPR-Cas system in Escherichia coli.

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR associated (cas) genes conform the CRISPR-Cas systems of various bacteria and archaea and produce degradation of invading nucleic acids containing sequences (protospacers) that are complementary to repeat intervening space...

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Bibliographic Details
Main Authors: Cristóbal Almendros, Noemí M Guzmán, César Díez-Villaseñor, Jesús García-Martínez, Francisco J M Mojica
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3506596?pdf=render