Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease

<p>Abstract</p> <p>Background</p> <p>Aβ deposits in the brains of patients with Alzheimer's disease (AD) are closely associated with innate immune responses such as activated microglia and increased cytokines. Accumulating evidence supports the hypothesis that inna...

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Bibliographic Details
Main Authors: Li Ling, Maxwell J Adam, Kim Hong-Duck, Jin Jing-Ji, Fukuchi Ken-ichiro
Format: Article
Language:English
Published: BMC 2008-05-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/5/1/23