Biodegradable PLGA-<i>b</i>-PEG Nanoparticles Induce T Helper 2 (Th2) Immune Responses and Sustained Antibody Titers via TLR9 Stimulation

Biodegradable PLGA-<i>b</i>-PEG Nanoparticles Induce T Helper 2 (Th2) Immune Responses and Sustained Antibody Titers via TLR9 Stimulation

Sustained immune responses, particularly antibody responses, are key for protection against many endemic infectious diseases. Antibody responses are often accompanied by T helper (Th) cell immunity. Herein we study small biodegradable poly (ethylene glycol)-<i>b</i>-poly (lactic-co-glyco...

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Bibliographic Details
Main Authors: Kirsty L. Wilson, Gregory P. Howard, Heather Coatsworth, Rhoel R. Dinglasan, Hai-Quan Mao, Magdalena Plebanski
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Vaccines
Subjects:
nanoparticle
adjuvant
vaccine
antibody
immune response
Online Access:https://www.mdpi.com/2076-393X/8/2/261

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