FENO AND ATOPY IN PEDIATRIC ASTHMA

Objectives. The aim of this study was to determine the manner in which the level of exhaled nitric oxide (FENO) infl uences the atopic status in children with asthma. Methods. The study included 92 asthmatic children (aged 5-18 years) admitted on the Pediatric Clinic of “Grigore Alexandrescu” Emer...

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Main Authors: Cristiana Stanciulescu, Mirela Chiru, Alina Oprea, Daniela Pacurar, Carmen Zapucioiu, Elena Petrisor, Dumitru Oraseanu
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2015-06-01
Series:Romanian Journal of Pediatrics
Subjects:
ige
Online Access:https://revistemedicale.amaltea.ro/Romanian_Journal_of_PEDIATRICS/Revista_Romana_de_PEDIATRIE-2015-Nr.2/EN/RJP_2015_2_EN_Art-06.pdf
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spelling doaj-3c9868b027fa487b9209a78f3c7b789a2021-09-02T19:22:31ZengAmaltea Medical Publishing HouseRomanian Journal of Pediatrics1454-03982069-61752015-06-0164213613910.37897/RJP.2015.2.6FENO AND ATOPY IN PEDIATRIC ASTHMACristiana Stanciulescu0Mirela Chiru1Alina Oprea2Daniela Pacurar3Carmen Zapucioiu4Elena Petrisor5Dumitru Oraseanu6“Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest“Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest; “Carol Davila” University of Medicine and Pharmacy, Bucharest“Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest“Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest; “Carol Davila” University of Medicine and Pharmacy, Bucharest“Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest; “Carol Davila” University of Medicine and Pharmacy, Bucharest“Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest“Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest; “Carol Davila” University of Medicine and Pharmacy, BucharestObjectives. The aim of this study was to determine the manner in which the level of exhaled nitric oxide (FENO) infl uences the atopic status in children with asthma. Methods. The study included 92 asthmatic children (aged 5-18 years) admitted on the Pediatric Clinic of “Grigore Alexandrescu” Emergency Clinical Hospital for Children. The atopic status was evaluated through anamnesis, clinical examination and laboratory determination of serum eosinophils and total Ig E. All children underwent measurement of FENO. Results. Children with atopic asthma had higher levels of FENO than children with nonatopic asthma. The FENO values correlate with eosinophilia and high values of immunoglobulin E. Conclusion. FENO is a useful marker for the evaluation of airway infl ammation in children with atopic asthma. https://revistemedicale.amaltea.ro/Romanian_Journal_of_PEDIATRICS/Revista_Romana_de_PEDIATRIE-2015-Nr.2/EN/RJP_2015_2_EN_Art-06.pdffenoeosinophiliaigeasthmaatopy
collection DOAJ
language English
format Article
sources DOAJ
author Cristiana Stanciulescu
Mirela Chiru
Alina Oprea
Daniela Pacurar
Carmen Zapucioiu
Elena Petrisor
Dumitru Oraseanu
spellingShingle Cristiana Stanciulescu
Mirela Chiru
Alina Oprea
Daniela Pacurar
Carmen Zapucioiu
Elena Petrisor
Dumitru Oraseanu
FENO AND ATOPY IN PEDIATRIC ASTHMA
Romanian Journal of Pediatrics
feno
eosinophilia
ige
asthma
atopy
author_facet Cristiana Stanciulescu
Mirela Chiru
Alina Oprea
Daniela Pacurar
Carmen Zapucioiu
Elena Petrisor
Dumitru Oraseanu
author_sort Cristiana Stanciulescu
title FENO AND ATOPY IN PEDIATRIC ASTHMA
title_short FENO AND ATOPY IN PEDIATRIC ASTHMA
title_full FENO AND ATOPY IN PEDIATRIC ASTHMA
title_fullStr FENO AND ATOPY IN PEDIATRIC ASTHMA
title_full_unstemmed FENO AND ATOPY IN PEDIATRIC ASTHMA
title_sort feno and atopy in pediatric asthma
publisher Amaltea Medical Publishing House
series Romanian Journal of Pediatrics
issn 1454-0398
2069-6175
publishDate 2015-06-01
description Objectives. The aim of this study was to determine the manner in which the level of exhaled nitric oxide (FENO) infl uences the atopic status in children with asthma. Methods. The study included 92 asthmatic children (aged 5-18 years) admitted on the Pediatric Clinic of “Grigore Alexandrescu” Emergency Clinical Hospital for Children. The atopic status was evaluated through anamnesis, clinical examination and laboratory determination of serum eosinophils and total Ig E. All children underwent measurement of FENO. Results. Children with atopic asthma had higher levels of FENO than children with nonatopic asthma. The FENO values correlate with eosinophilia and high values of immunoglobulin E. Conclusion. FENO is a useful marker for the evaluation of airway infl ammation in children with atopic asthma.
topic feno
eosinophilia
ige
asthma
atopy
url https://revistemedicale.amaltea.ro/Romanian_Journal_of_PEDIATRICS/Revista_Romana_de_PEDIATRIE-2015-Nr.2/EN/RJP_2015_2_EN_Art-06.pdf
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