Expression of Wnt/β-Catenin Signaling Pathway and Its Regulatory Role in Type I Collagen with TGF-β1 in Scleral Fibroblasts from an Experimentally Induced Myopia Guinea Pig Model
Background. To investigate Wnt/β-catenin signaling pathway expression and its regulation of type I collagen by TGF-β1 in scleral fibroblasts from form-deprivation myopia (FDM) guinea pig model. Methods. Wnt isoforms were examined using genome microarrays. Scleral fibroblasts from FDM group and self-...
Main Authors: | Min Li, Ying Yuan, Qingzhong Chen, Rao Me, Qing Gu, Yunjie Yu, Minjie Sheng, Bilian Ke |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2016-01-01
|
Series: | Journal of Ophthalmology |
Online Access: | http://dx.doi.org/10.1155/2016/5126560 |
Similar Items
-
Endoplasmic Reticulum Stress Regulates Scleral Remodeling in a Guinea Pig Model of Form-Deprivation Myopia
by: Chengcheng Zhu, et al.
Published: (2020-01-01) -
Induced myopia in the guinea pig: scleral myofibroblasts and biomechanics
by: Backhouse, Simon
Published: (2009) -
Scleral TGF-β1 and Smad3 expression is altered by TCM Bu Jing Yi Shi Tablets in guinea pigs with form-deprivation myopia
by: Ya Mo, et al.
Published: (2016-04-01) -
The Effects of Scleral Collagen Cross-Linking Using Glyceraldehyde on the Progression of Form-Deprived Myopia in Guinea Pigs
by: Yanhua Chu, et al.
Published: (2016-01-01) -
Activation of WNT/β-catenin signaling in pulmonary fibroblasts by TGF-β₁ is increased in chronic obstructive pulmonary disease.
by: Hoeke A Baarsma, et al.
Published: (2011-01-01)