Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review

D-aspartate, a natural and endogenous amino acid, widely exists in animal tissues and can be synthesized through aspartate racemase and transformed by D-aspartate oxidase (DDO). D-aspartate mainly serves as a neurotransmitter and has been demonstrated to exhibit various physiological functions, incl...

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Main Authors:	Yuying Li, Hui Han, Jie Yin, Tiejun Li, Yulong Yin
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2018-09-01
Series:	Animal Nutrition
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405654517301932

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spelling	doaj-3c8de3670228469d9664638da59ced612021-04-02T09:43:34ZengKeAi Communications Co., Ltd.Animal Nutrition2405-65452018-09-0143311315Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-reviewYuying Li0Hui Han1Jie Yin2Tiejun Li3Yulong Yin4Key Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China; University of Chinese Academy of Sciences, Beijing 100039, ChinaKey Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China; University of Chinese Academy of Sciences, Beijing 100039, ChinaKey Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China; University of Chinese Academy of Sciences, Beijing 100039, ChinaKey Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China; Hunan Co-Innovation Center of Animal Production Safety, Changsha 410128, China; Corresponding authors.Key Laboratory of Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central, Ministry of Agriculture, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China; Hunan Co-Innovation Center of Animal Production Safety, Changsha 410128, China; Corresponding authors.D-aspartate, a natural and endogenous amino acid, widely exists in animal tissues and can be synthesized through aspartate racemase and transformed by D-aspartate oxidase (DDO). D-aspartate mainly serves as a neurotransmitter and has been demonstrated to exhibit various physiological functions, including nutritional potential, regulation on reproduction and hormone biology, and neuron protection. This article mainly reviews the synthesis, racemization, and physiological functions of D-aspartate with emphasis on the potential in diseases. Keywords: D-aspartate, Biosynthesis, Racemization, Nutrition, Functionshttp://www.sciencedirect.com/science/article/pii/S2405654517301932
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Yuying Li Hui Han Jie Yin Tiejun Li Yulong Yin
spellingShingle	Yuying Li Hui Han Jie Yin Tiejun Li Yulong Yin Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review Animal Nutrition
author_facet	Yuying Li Hui Han Jie Yin Tiejun Li Yulong Yin
author_sort	Yuying Li
title	Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review
title_short	Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review
title_full	Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review
title_fullStr	Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review
title_full_unstemmed	Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review
title_sort	role of d-aspartate on biosynthesis, racemization, and potential functions: a mini-review
publisher	KeAi Communications Co., Ltd.
series	Animal Nutrition
issn	2405-6545
publishDate	2018-09-01
description	D-aspartate, a natural and endogenous amino acid, widely exists in animal tissues and can be synthesized through aspartate racemase and transformed by D-aspartate oxidase (DDO). D-aspartate mainly serves as a neurotransmitter and has been demonstrated to exhibit various physiological functions, including nutritional potential, regulation on reproduction and hormone biology, and neuron protection. This article mainly reviews the synthesis, racemization, and physiological functions of D-aspartate with emphasis on the potential in diseases. Keywords: D-aspartate, Biosynthesis, Racemization, Nutrition, Functions
url	http://www.sciencedirect.com/science/article/pii/S2405654517301932
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Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review

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