Role of D-aspartate on biosynthesis, racemization, and potential functions: A mini-review

D-aspartate, a natural and endogenous amino acid, widely exists in animal tissues and can be synthesized through aspartate racemase and transformed by D-aspartate oxidase (DDO). D-aspartate mainly serves as a neurotransmitter and has been demonstrated to exhibit various physiological functions, incl...

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Bibliographic Details
Main Authors: Yuying Li, Hui Han, Jie Yin, Tiejun Li, Yulong Yin
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2018-09-01
Series:Animal Nutrition
Online Access:http://www.sciencedirect.com/science/article/pii/S2405654517301932
Description
Summary:D-aspartate, a natural and endogenous amino acid, widely exists in animal tissues and can be synthesized through aspartate racemase and transformed by D-aspartate oxidase (DDO). D-aspartate mainly serves as a neurotransmitter and has been demonstrated to exhibit various physiological functions, including nutritional potential, regulation on reproduction and hormone biology, and neuron protection. This article mainly reviews the synthesis, racemization, and physiological functions of D-aspartate with emphasis on the potential in diseases. Keywords: D-aspartate, Biosynthesis, Racemization, Nutrition, Functions
ISSN:2405-6545