FOXN1GFP/w Reporter hESCs Enable Identification of Integrin-β4, HLA-DR, and EpCAM as Markers of Human PSC-Derived FOXN1+ Thymic Epithelial Progenitors

FOXN1GFP/w Reporter hESCs Enable Identification of Integrin-β4, HLA-DR, and EpCAM as Markers of Human PSC-Derived FOXN1+ Thymic Epithelial Progenitors

Thymic epithelial cells (TECs) play a critical role in T cell maturation and tolerance induction. The generation of TECs from in vitro differentiation of human pluripotent stem cells (PSCs) provides a platform on which to study the mechanisms of this interaction and has implications for immune recon...

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Bibliographic Details
Main Authors: Chew-Li Soh, Antonietta Giudice, Robert A. Jenny, David A. Elliott, Tanya Hatzistavrou, Suzanne J. Micallef, Korosh Kianizad, Natalie Seach, Juan Carlos Zúñiga-Pflücker, Ann P. Chidgey, Alan Trounson, Susan K. Nilsson, David N. Haylock, Richard L. Boyd, Andrew G. Elefanty, Edouard G. Stanley
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114001167

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