The C. difficile clnRAB operon initiates adaptations to the host environment in response to LL-37.
To cause disease, Clostridioides (Clostridium) difficile must resist killing by innate immune effectors in the intestine, including the host antimicrobial peptide, cathelicidin (LL-37). The mechanisms that enable C. difficile to adapt to the intestine in the presence of antimicrobial peptides are un...
Main Authors: | Emily C Woods, Adrianne N Edwards, Kevin O Childress, Joshua B Jones, Shonna M McBride |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-08-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC6117091?pdf=render |
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