Nitric Oxide Donors and Selective Carbonic Anhydrase Inhibitors: A Dual Pharmacological Approach for the Treatment of Glaucoma, Cancer and Osteoporosis

Nitric Oxide Donors and Selective Carbonic Anhydrase Inhibitors: A Dual Pharmacological Approach for the Treatment of Glaucoma, Cancer and Osteoporosis

Due to the recognized biological role of nitric oxide (NO) donating derivatives and of selective inhibitors of specific human carbonic anhydrase isoforms (CA, EC 4.2.1.1), promising compounds having an aromatic/heterocyclic primary sulfonamide and functionalized with NO-releasing moieties have been...

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Bibliographic Details
Main Authors: Simone Carradori, Adriano Mollica, Celeste De Monte, Arianna Granese, Claudiu T. Supuran
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Molecules
Subjects:
NO donors
selective carbonic anhydrase inhibitors
glaucoma
cancer
osteoporosis
dual pharmacological activity
Online Access:http://www.mdpi.com/1420-3049/20/4/5667

Internet

http://www.mdpi.com/1420-3049/20/4/5667

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