α2β1 integrin affects metastatic potential of ovarian carcinoma spheroids by supporting disaggregation and proteolysis

<p>Abstract</p> <p>Background</p> <p>Ovarian cancer is characterized by a wide-spread intra-abdominal metastases which represents a major clinical hurdle in the prognosis and management of the disease. A significant proportion of ovarian cancer cells in peritoneal ascit...

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Bibliographic Details
Main Authors: Ackland Margaret, Shield Kristy, Riley Clyde, Quinn Michael, Rice Gregory, Ahmed Nuzhat
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2007-01-01
Series:Journal of Carcinogenesis
Online Access:http://www.carcinogenesis.com/content/6/1/11