Lipid–peptide bioconjugation through pyridyl disulfide reaction chemistry and its application in cell targeting and drug delivery

Lipid–peptide bioconjugation through pyridyl disulfide reaction chemistry and its application in cell targeting and drug delivery

Abstract Background The design of efficient drug delivery vectors requires versatile formulations able to simultaneously direct a multitude of molecular targets and to bypass the endosomal recycling pathway of cells. Liposomal-based vectors need the decoration of the lipid surface with specific pept...

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Bibliographic Details
Main Authors: Diego de la Fuente-Herreruela, Ajay K. Monnappa, Mónica Muñoz-Úbeda, Aarón Morallón-Piña, Eduardo Enciso, Luis Sánchez, Fabrice Giusti, Paolo Natale, Iván López-Montero
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Nanobiotechnology
Subjects:
Smart liposomes
Disulfide bonds
Targeting peptide
GALA
Endosomal escape
Online Access:http://link.springer.com/article/10.1186/s12951-019-0509-8

Internet

http://link.springer.com/article/10.1186/s12951-019-0509-8

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