The Impact of Lipoproteins on Wound Healing: Topical HDL Therapy Corrects Delayed Wound Healing in Apolipoprotein E Deficient Mice

The Impact of Lipoproteins on Wound Healing: Topical HDL Therapy Corrects Delayed Wound Healing in Apolipoprotein E Deficient Mice

Chronic non-healing wounds lead to considerable morbidity and mortality. Pleiotropic effects of high density lipoproteins (HDL) may beneficially affect wound healing. The objectives of this murine study were: (1) to investigate the hypothesis that hypercholesterolemia induces impaired wound healing...

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Bibliographic Details
Main Authors: Stephanie C. Gordts, Ilayaraja Muthuramu, Ruhul Amin, Frank Jacobs, Bart De Geest
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Pharmaceuticals
Subjects:
hypercholesterolemia
high density lipoproteins
LDL receptor gene transfer
wound healing
topical therapy
Online Access:http://www.mdpi.com/1424-8247/7/4/419

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