Paradoxical inhibition of cellular protein expression by proteasome inhibitors
Proteasome inhibitors are used as anticancer drugs, however, the precise mechanisms of their selective activity against cancer cells are not understood well. While proteasome inhibitors stabilize the majority of cellular proteins through inhibition of proteasome activity, they also paradoxically dow...
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| Format: | Article |
| Language: | English |
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De Gruyter
2012-12-01
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| Series: | Biomolecular Concepts |
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| Online Access: | https://doi.org/10.1515/bmc-2012-0029 |