Nanomicellar Formulation of Clotrimazole Improves Its Antitumor Action toward Human Breast Cancer Cells.

Nanomicellar Formulation of Clotrimazole Improves Its Antitumor Action toward Human Breast Cancer Cells.

Although demonstrated as a selective anticancer drug, the clinical use of clotrimazole (CTZ) is limited due to its low solubility in hydrophilic fluids. Thus, we prepared a water-soluble nanomicellar formulation of CTZ (nCTZ) and tested on the human breast cancer cell line MCF-7 biology.CTZ was nano...

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Bibliographic Details
Main Authors: Mariah C Marcondes, Anne C S Fernandes, Ivaldo Itabaiana, Rodrigo O M A de Souza, Mauro Sola-Penna, Patricia Zancan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4476588?pdf=render

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http://europepmc.org/articles/PMC4476588?pdf=render

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