Detection of the transforming <it>AKT1 </it>mutation E17K in non-small cell lung cancer by high resolution melting
<p>Abstract</p> <p>Background</p> <p>A recurrent somatic mutation, E17K, in the pleckstrin homology domain of the <it>AKT1 </it>gene, has been recently described in breast, colorectal, and ovarian cancers. AKT1 is a pivotal mediator of signalling pathways in...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-05-01
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Series: | BMC Research Notes |
Online Access: | http://www.biomedcentral.com/1756-0500/1/14 |