A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuoles
Replication of Toxoplasma gondii requires replication and distribution of essential organelles such as micronemes. Here, Periz et al. show that micronemes are recycled from the mother to the forming daughter cells using a highly dynamic F-actin network that supports multidirectional vesicle transpor...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2019-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-12136-2 |
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doaj-3c5a5580b357461881dd82599df5e81a2021-05-11T11:28:55ZengNature Publishing GroupNature Communications2041-17232019-09-0110111610.1038/s41467-019-12136-2A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuolesJavier Periz0Mario Del Rosario1Alexandra McStea2Simon Gras3Colin Loney4Lin Wang5Marisa L. Martin-Fernandez6Markus Meissner7Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity & Inflammation, University of GlasgowWellcome Centre for Integrative Parasitology, Institute of Infection, Immunity & Inflammation, University of GlasgowCentral Laser Facility, Research Complex at Harwell Science & Technology Facilities CouncilExperimental Parasitology, Department for Veterinary Sciences, Ludwig-Maximilians-University MunichMRC-University of Glasgow Centre for Virus Research, Sir Michael Stoker BuildingCentral Laser Facility, Research Complex at Harwell Science & Technology Facilities CouncilCentral Laser Facility, Research Complex at Harwell Science & Technology Facilities CouncilWellcome Centre for Integrative Parasitology, Institute of Infection, Immunity & Inflammation, University of GlasgowReplication of Toxoplasma gondii requires replication and distribution of essential organelles such as micronemes. Here, Periz et al. show that micronemes are recycled from the mother to the forming daughter cells using a highly dynamic F-actin network that supports multidirectional vesicle transport.https://doi.org/10.1038/s41467-019-12136-2 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Javier Periz Mario Del Rosario Alexandra McStea Simon Gras Colin Loney Lin Wang Marisa L. Martin-Fernandez Markus Meissner |
| spellingShingle |
Javier Periz Mario Del Rosario Alexandra McStea Simon Gras Colin Loney Lin Wang Marisa L. Martin-Fernandez Markus Meissner A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuoles Nature Communications |
| author_facet |
Javier Periz Mario Del Rosario Alexandra McStea Simon Gras Colin Loney Lin Wang Marisa L. Martin-Fernandez Markus Meissner |
| author_sort |
Javier Periz |
| title |
A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuoles |
| title_short |
A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuoles |
| title_full |
A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuoles |
| title_fullStr |
A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuoles |
| title_full_unstemmed |
A highly dynamic F-actin network regulates transport and recycling of micronemes in Toxoplasma gondii vacuoles |
| title_sort |
highly dynamic f-actin network regulates transport and recycling of micronemes in toxoplasma gondii vacuoles |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2019-09-01 |
| description |
Replication of Toxoplasma gondii requires replication and distribution of essential organelles such as micronemes. Here, Periz et al. show that micronemes are recycled from the mother to the forming daughter cells using a highly dynamic F-actin network that supports multidirectional vesicle transport. |
| url |
https://doi.org/10.1038/s41467-019-12136-2 |
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