Tumor Temporal Proteome Profiling Reveals the Immunological Triple Offensive Induced by Synthetic Anti-Cancer Salmonella

Tumor Temporal Proteome Profiling Reveals the Immunological Triple Offensive Induced by Synthetic Anti-Cancer Salmonella

The engineered “obligate” anaerobic Salmonella typhimurium strain YB1 shows a prominent ability to repress tumor growth and metastasis, which has great potential as a novel cancer immunotherapy. However, the antitumor mechanism of YB1 remains unelucidated. To resolve the proteome dynamics induced by...

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Bibliographic Details
Main Authors: Shuxin Yang, Wenjuan Zhao, Muchun Zhu, Huijuan Hu, Weijie Wang, Zhongsheng Zang, Meiling Jin, Jiacheng Bi, Jiandong Huang, Chenli Liu, Xuefei Li, Peng Yin, Nan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
quantitative proteomics
cancer immunotherapy
engineered Salmonella
blood coagulation
phagocytosis
antitumor T cell response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.712936/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.712936/full

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