BARIATRIC SURGERY METABOLIC EFFECTS IN OBESE INDIVIDUALS ASSOCIATING INSULIN RESISTANCE STATUS

• Main Authors: Paula Dejeu, Viorel Dejeu, Danut Dejeu, Marius Bembea
• Format: Article
• Language: English
• Published: Amaltea Medical Publishing House 2019-12-01
• Series: Romanian Medical Journal
• Subjects: insulin resistance; homa index; obesity; bariatric surgery
• Online Access: https://revistemedicale.amaltea.ro/Romanian_MEDICAL_Journal/Revista_MEDICALA_ROMANA-2019-Nr.4/RMJ_2019_4_Art-19.pdf

Background and aims. Metabolic syndrome or insulin-resistance syndrome is an obesity related condition that increases the risk of developing type 2 diabetes mellitus over time. In this prospective study, overweight and obese individuals were assessed for insulin-resistance status by the HOMA indexes. Material and methods. 48 bariatric patients associating metabolic syndrome were assessed before and 6 months after the surgery procedure (gastric sleeve, gastric by-pass). The assessment included the following laboratory blood tests: glucose, insulin, HOMA1 index and HOMA2 index before meal. Results. There was a significant improvement of insulin resistance status in obese patients who underwent bariatric surgery. Conclusions. Insulin resistance status in obese individuals improves significantly after bariatric treatment.