The Study of Diagnostic Efficacy of Nerve Conduction Study Parameters in Cervical Radiculopathy
Background: Cervical Radiculopathy (CR) is a neurologic condition characterised by dysfunction of a cervical spinal nerve, the roots of the nerve, or both. Diagnostic criteria for CR are not well defined, and no universally accepted criteria for its diagnosis have been established. Clinical exam...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
JCDR Research and Publications Private Limited
2013-12-01
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Series: | Journal of Clinical and Diagnostic Research |
Subjects: | |
Online Access: | https://jcdr.net/articles/PDF/3731/8-%207545_F(P)_PF1(Pr_P)_FA(T)_PF2(Si_PP).pdf |
Summary: | Background: Cervical Radiculopathy (CR) is a neurologic
condition characterised by dysfunction of a cervical spinal nerve,
the roots of the nerve, or both. Diagnostic criteria for CR are not
well defined, and no universally accepted criteria for its diagnosis
have been established. Clinical examination, radiological imaging
and electrophysiologic evaluation are the different modalities to
diagnose CR. The incidence of Cervical Spondylosis and related
conditions is increasing in the present scenario and the use of
radiologic examination is time consuming and uneconomical for
the common Indian setup. Thus, there is a definite need to establish
a cost effective, reliable, and accurate means for establishing the
diagnosis of cervical radiculopathy. Electrodiagnostic tests are
the closest to fulfill these criteria.
Aim: To evaluate diagnostic utility of various motor and sensory
nerve conduction study parameters in cervical radiculopathy.
Setting and Design: It was a cross-sectional study conducted
on 100 subjects of age > 40 years.
Material and Methods: The consecutive patients clinically
diagnosed to have cervical radiculopathy, referred from
department of Orthopaedics were prospectively recruited for
the motor and sensory nerve conduction study using RMS EMG
EP Mark-II. Parameters studied were Compound Muscle Action
Potential (CMAP), Distal Motor Latency (DML) and Conduction
Velocity (CV) for motor nerves and Sensory Nerve Action Potential
(SNAP) and CV for sensory nerves.
Statistical Analysis: Study observations and results were
analysed to find the Specificity, Sensitivity, Positive Predictive
Value and Negative Predictive Value using SPSS 16.0.
Results: Among various motor nerve conduction parameters
CMAP was found to be more sensitive with high positive
predicative value. CV was found to have greater specificity
and DML had least negative predictive value. Sensory nerve
conduction parameters were found to have less sensitivity but
higher specificity as compared to motor parameters.
Conclusion: Nerve conduction studies are useful supportive
diagnostic tool for suspected cervical radiculopathy as they are
found to have reliable sensitivity and specificity. |
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ISSN: | 2249-782X 0973-709X |