Transcriptome Study of an Exophiala dermatitidis PKS1 Mutant on an ex Vivo Skin Model: Is Melanin Important for Infection?

Transcriptome Study of an Exophiala dermatitidis PKS1 Mutant on an ex Vivo Skin Model: Is Melanin Important for Infection?

The black yeast Exophiala dermatitidis is a polyextremophilic human pathogen, especially known for growing in man-made extreme environments. Reported diseases caused by this fungus range from benign cutaneous to systemic infections with 40% fatality rate. While the number of cases steadily increases...

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Bibliographic Details
Main Authors: Caroline Poyntner, Ursula Mirastschijski, Katja Sterflinger, Hakim Tafer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
melanin
black yeast
Exophiala dermatitidis
PKS1
skin model
virulence
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01457/full

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