A comparison of lipoprotein lipase activity and adipocyte differentiation in growing male rats

During adipose tissue development changes in lipoprotein lipase activity per adipocyte precede significant changes in fat cell size. Lipoprotein lipase activity per adipocyte increases fourfold from the second to seventh postnatal week. Furthermore, when isolated adipocytes and stromal—vascular cell...

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Bibliographic Details
Main Authors:	E Hietanen, M R C Greenwood
Format:	Article
Language:	English
Published:	Elsevier 1977-07-01
Series:	Journal of Lipid Research
Subjects:	adipose tissue isolated fat cells isolated stromal-vascular cells adipose tissue cellularity
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520416657

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spelling	doaj-3c03768f7ea7495998df9250a63269eb2021-04-24T05:53:52ZengElsevierJournal of Lipid Research0022-22751977-07-01184480490A comparison of lipoprotein lipase activity and adipocyte differentiation in growing male ratsE Hietanen0M R C Greenwood1Institute of Human Nutrition and Department of Genetics and Human Development, Columbia University, College of Physicians and Surgeons, New York, NY 10032; Department of Physiology, University of Turku, Turku, FinlandInstitute of Human Nutrition and Department of Genetics and Human Development, Columbia University, College of Physicians and Surgeons, New York, NY 10032During adipose tissue development changes in lipoprotein lipase activity per adipocyte precede significant changes in fat cell size. Lipoprotein lipase activity per adipocyte increases fourfold from the second to seventh postnatal week. Furthermore, when isolated adipocytes and stromal—vascular cells are prepared by collagenase digestion of adipose tissue, there is a progressive shift in enzyme activity during development from the stromal-vascular compartment to the adipocyte fraction. The data support the concept that during normal development a “bed” of preadipocytes is synthesized during the suckling period. The data further suggest a regulatory role for lipoprotein lipase in the control of “lipid-filling” during early postnatal development.http://www.sciencedirect.com/science/article/pii/S0022227520416657adipose tissueisolated fat cellsisolated stromal-vascular cellsadipose tissue cellularity
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	E Hietanen M R C Greenwood
spellingShingle	E Hietanen M R C Greenwood A comparison of lipoprotein lipase activity and adipocyte differentiation in growing male rats Journal of Lipid Research adipose tissue isolated fat cells isolated stromal-vascular cells adipose tissue cellularity
author_facet	E Hietanen M R C Greenwood
author_sort	E Hietanen
title	A comparison of lipoprotein lipase activity and adipocyte differentiation in growing male rats
title_short	A comparison of lipoprotein lipase activity and adipocyte differentiation in growing male rats
title_full	A comparison of lipoprotein lipase activity and adipocyte differentiation in growing male rats
title_fullStr	A comparison of lipoprotein lipase activity and adipocyte differentiation in growing male rats
title_full_unstemmed	A comparison of lipoprotein lipase activity and adipocyte differentiation in growing male rats
title_sort	comparison of lipoprotein lipase activity and adipocyte differentiation in growing male rats
publisher	Elsevier
series	Journal of Lipid Research
issn	0022-2275
publishDate	1977-07-01
description	During adipose tissue development changes in lipoprotein lipase activity per adipocyte precede significant changes in fat cell size. Lipoprotein lipase activity per adipocyte increases fourfold from the second to seventh postnatal week. Furthermore, when isolated adipocytes and stromal—vascular cells are prepared by collagenase digestion of adipose tissue, there is a progressive shift in enzyme activity during development from the stromal-vascular compartment to the adipocyte fraction. The data support the concept that during normal development a “bed” of preadipocytes is synthesized during the suckling period. The data further suggest a regulatory role for lipoprotein lipase in the control of “lipid-filling” during early postnatal development.
topic	adipose tissue isolated fat cells isolated stromal-vascular cells adipose tissue cellularity
url	http://www.sciencedirect.com/science/article/pii/S0022227520416657
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A comparison of lipoprotein lipase activity and adipocyte differentiation in growing male rats

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