Environmental enrichment combined with fasudil promotes motor function recovery and axonal regeneration after stroke

Environmental enrichment combined with fasudil promotes motor function recovery and axonal regeneration after stroke

Fasudil, a Rho-associated protein kinase (ROCK) inhibitor, has a protective effect on the central nervous system. In addition, environmental enrichment is a promising technique for inducing the recovery of motor impairments in ischemic stroke models. The present study aimed to explore whether enviro...

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Bibliographic Details
Main Authors: Yi-Tong Zhu, Qun Zhang, Hong-Yu Xie, Ke-Wei Yu, Gao-Jing Xu, Si-Yue Li, Yi Wu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
axon regeneration; biotinylated dextran amines; environmental enrichment; fasudil; growth-associated protein 43; ischemic stroke; motor recovery; nissl bodies; rho/rock pathway
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=12;spage=2512;epage=2520;aulast=Zhu

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