Modulatory Impact of Adipose-Derived Mesenchymal Stem Cells of Ankylosing Spondylitis Patients on T Helper Cell Differentiation

Modulatory Impact of Adipose-Derived Mesenchymal Stem Cells of Ankylosing Spondylitis Patients on T Helper Cell Differentiation

The domination of pro-inflammatory Th subsets (Th1, Th17) is characteristic of ankylosing spondylitis (AS). Mesenchymal stem cells (MSC) were reported to normalize Th imbalance, but whether MSCs from AS adipose tissue (AS/ASCs) possess such properties is unknown. We examined AS/ASCs’ impact on Th-ce...

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Bibliographic Details
Main Authors: Ewa Kuca-Warnawin, Iwona Janicka, Krzysztof Bonek, Ewa Kontny
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
ankylosing spondylitis
adipose-derived mesenchymal stem cells
T helper cell subsets
transcription factors
cytokines
Online Access:https://www.mdpi.com/2073-4409/10/2/280

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