NME3 Regulates Mitochondria to Reduce ROS-Mediated Genome Instability

NME3 is a member of the nucleoside diphosphate kinase (NDPK) family that binds to the mitochondrial outer membrane to stimulate mitochondrial fusion. In this study, we showed that NME3 knockdown delayed DNA repair without reducing the cellular levels of nucleotide triphosphates. Further analyses rev...

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Bibliographic Details
Main Authors: Chih-Wei Chen, Ning Tsao, Wei Zhang, Zee-Fen Chang
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/14/5048