Contemporary psychosurgery: Deep brain stimulation for the treatment of refractory depression
The aim of this review is to present the use of deep brain stimulation in the treatment of resistant depression and to summarize the available clinical data stemming from this area. The need for new therapeutic interventions in the treatment of depression is emphasized, followed by a short overview...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Slovenian Medical Association
2010-05-01
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| Series: | Zdravniški Vestnik |
| Online Access: | http://vestnik.szd.si/index.php/ZdravVest/article/view/261 |
| Summary: | The aim of this review is to present the use of
deep brain stimulation in the treatment of resistant
depression and to summarize the available
clinical data stemming from this area. The need
for new therapeutic interventions in the treatment
of depression is emphasized, followed by
a short overview of the history of psychosurgery.
A tentative explanation of the mechanisms of
therapeutic effects of deep brain stimulation is
presented. Current understanding of the mechanisms
of deep brain stimulation in two brain regions
is provided to account for the use of this
method in resistant depression. Results of clinical
trials using deep brain stimulation for the
treatment of depression are reviewed. In conclusion,
the authors discuss the role of psychosurgery
in contemporary psychiatric treatment,
emphasizing the need for further research. |
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| ISSN: | 1318-0347 1581-0224 |