Yessotoxin, a Promising Therapeutic Tool

Yessotoxin, a Promising Therapeutic Tool

Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cell...

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Bibliographic Details
Main Authors: Amparo Alfonso, Mercedes R. Vieytes, Luis M. Botana
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Marine Drugs
Subjects:
yessotoxin (YTX)
apoptosis
autophagy
cellular death
signal transduction
cytoskeleton
immune system
Alzheimer
glucose metabolism
Online Access:http://www.mdpi.com/1660-3397/14/2/30
Description
Summary:Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cells, cytoskeleton or activation of different cellular death types have been published as consequence of YTX exposure. This review summarizes the main intracellular pathways modulated by YTX and their pharmacological and therapeutic implications.
ISSN:1660-3397

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