Application of protein chip and mass spectrometry in dry eye syndromes

Dry eye syndrome is one of the most common ophthalmology diseases. With the improvement of non-invasive tear extraction methods, tear protein analysis becomes a best choice for the diagnosis and evaluation of efficacy of dry eye. Methods that have been used for tear proteomics research include prote...

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Main Authors:	Yan-Ting Yang, Dan Zhang, Jue Hong, Jie Liu, Xiao-Qing Dong, Xiao-Cong Guo, Xiao-Peng Ma
Format:	Article
Language:	English
Published:	Press of International Journal of Ophthalmology (IJO PRESS) 2020-09-01
Series:	Guoji Yanke Zazhi
Subjects:	dry eye syndromes tear protein chip mass spectrometry
Online Access:	http://ies.ijo.cn/cn_publish/2020/9/202009017.pdf

id	doaj-3bdde176846e4f358f5404a4c2223ce4
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spelling	doaj-3bdde176846e4f358f5404a4c2223ce42020-11-25T03:42:13ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232020-09-012091551155510.3980/j.issn.1672-5123.2020.9.17Application of protein chip and mass spectrometry in dry eye syndromesYan-Ting Yang0Dan Zhang1Jue Hong2Jie Liu3Xiao-Qing Dong4Xiao-Cong Guo5Xiao-Peng Ma6Shanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, ChinaShanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, ChinaShanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, ChinaShanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, ChinaShanghai University of Traditional Chinese Medicine, Shanghai 201203, ChinaShanghai University of Traditional Chinese Medicine, Shanghai 201203, ChinaShanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, China; Shanghai University of Traditional Chinese Medicine, Shanghai 201203, ChinaDry eye syndrome is one of the most common ophthalmology diseases. With the improvement of non-invasive tear extraction methods, tear protein analysis becomes a best choice for the diagnosis and evaluation of efficacy of dry eye. Methods that have been used for tear proteomics research include protein chip technology and mass spectrometry. The relationship between the protein in the tear fluid and its concentration and different pathological conditions has important value in the research of dry eye syndromes. This article reviews the latest developments in the field, the application of tear proteomics research and current practical issues,it will provide highlights for the understanding of molecular mechanism of dry eye syndromes and benefits for potential molecular diagnosis of dry eye syndromes in the future.http://ies.ijo.cn/cn_publish/2020/9/202009017.pdfdry eye syndromestearprotein chipmass spectrometry
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Yan-Ting Yang Dan Zhang Jue Hong Jie Liu Xiao-Qing Dong Xiao-Cong Guo Xiao-Peng Ma
spellingShingle	Yan-Ting Yang Dan Zhang Jue Hong Jie Liu Xiao-Qing Dong Xiao-Cong Guo Xiao-Peng Ma Application of protein chip and mass spectrometry in dry eye syndromes Guoji Yanke Zazhi dry eye syndromes tear protein chip mass spectrometry
author_facet	Yan-Ting Yang Dan Zhang Jue Hong Jie Liu Xiao-Qing Dong Xiao-Cong Guo Xiao-Peng Ma
author_sort	Yan-Ting Yang
title	Application of protein chip and mass spectrometry in dry eye syndromes
title_short	Application of protein chip and mass spectrometry in dry eye syndromes
title_full	Application of protein chip and mass spectrometry in dry eye syndromes
title_fullStr	Application of protein chip and mass spectrometry in dry eye syndromes
title_full_unstemmed	Application of protein chip and mass spectrometry in dry eye syndromes
title_sort	application of protein chip and mass spectrometry in dry eye syndromes
publisher	Press of International Journal of Ophthalmology (IJO PRESS)
series	Guoji Yanke Zazhi
issn	1672-5123 1672-5123
publishDate	2020-09-01
description	Dry eye syndrome is one of the most common ophthalmology diseases. With the improvement of non-invasive tear extraction methods, tear protein analysis becomes a best choice for the diagnosis and evaluation of efficacy of dry eye. Methods that have been used for tear proteomics research include protein chip technology and mass spectrometry. The relationship between the protein in the tear fluid and its concentration and different pathological conditions has important value in the research of dry eye syndromes. This article reviews the latest developments in the field, the application of tear proteomics research and current practical issues,it will provide highlights for the understanding of molecular mechanism of dry eye syndromes and benefits for potential molecular diagnosis of dry eye syndromes in the future.
topic	dry eye syndromes tear protein chip mass spectrometry
url	http://ies.ijo.cn/cn_publish/2020/9/202009017.pdf
work_keys_str_mv	AT yantingyang applicationofproteinchipandmassspectrometryindryeyesyndromes AT danzhang applicationofproteinchipandmassspectrometryindryeyesyndromes AT juehong applicationofproteinchipandmassspectrometryindryeyesyndromes AT jieliu applicationofproteinchipandmassspectrometryindryeyesyndromes AT xiaoqingdong applicationofproteinchipandmassspectrometryindryeyesyndromes AT xiaocongguo applicationofproteinchipandmassspectrometryindryeyesyndromes AT xiaopengma applicationofproteinchipandmassspectrometryindryeyesyndromes
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Application of protein chip and mass spectrometry in dry eye syndromes

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