Prevalence of Fractures and Diagnostic Accuracy of Emergency X-ray in Older Adults Sustaining a Low-Energy Fall: A Retrospective Study

Background: Plain radiography (XR) series are standard of care for detection of fall-related fractures in older patients with low-energy falls (LEF) in the emergency department (ED). We have investigated the prevalence of fractures and diagnostic accuracy of XR imaging in the ED. Methods: 2839 patie...

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Main Authors: Alina Lampart, Isabelle Arnold, Nina Mäder, Sandra Niedermeier, Armin Escher, Robert Stahl, Christoph Trumm, Christian Kammerlander, Wolfgang Böcker, Christian H. Nickel, Roland Bingisser, Vera Pedersen
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/9/1/97
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spelling doaj-3bd7965aaa2e4e5f96267e37c7d126212020-11-25T02:18:06ZengMDPI AGJournal of Clinical Medicine2077-03832019-12-01919710.3390/jcm9010097jcm9010097Prevalence of Fractures and Diagnostic Accuracy of Emergency X-ray in Older Adults Sustaining a Low-Energy Fall: A Retrospective StudyAlina Lampart0Isabelle Arnold1Nina Mäder2Sandra Niedermeier3Armin Escher4Robert Stahl5Christoph Trumm6Christian Kammerlander7Wolfgang Böcker8Christian H. Nickel9Roland Bingisser10Vera Pedersen11Department of Emergency Medicine, University Hospital Basel, Petersgraben 2, 4031 Basel, SwitzerlandDepartment of Emergency Medicine, University Hospital Basel, Petersgraben 2, 4031 Basel, SwitzerlandDepartment of Emergency Medicine, University Hospital Basel, Petersgraben 2, 4031 Basel, SwitzerlandDepartment for General, Trauma and Reconstructive Surgery, Ludwig Maximilian University Munich, Marchioninstr. 15, 81377 Munich, GermanyDepartment of Radiology, University Hospital Basel, Petersgraben 2, 4031 Basel, SwitzerlandInstitute of Diagnostic and Interventional Neuroradiology, Ludwig Maximilian University Munich, Marchioninstr. 15, 81377 Munich, GermanyInstitute of Diagnostic and Interventional Neuroradiology, Ludwig Maximilian University Munich, Marchioninstr. 15, 81377 Munich, GermanyDepartment for General, Trauma and Reconstructive Surgery, Ludwig Maximilian University Munich, Marchioninstr. 15, 81377 Munich, GermanyDepartment for General, Trauma and Reconstructive Surgery, Ludwig Maximilian University Munich, Marchioninstr. 15, 81377 Munich, GermanyDepartment of Emergency Medicine, University Hospital Basel, Petersgraben 2, 4031 Basel, SwitzerlandDepartment of Emergency Medicine, University Hospital Basel, Petersgraben 2, 4031 Basel, SwitzerlandDepartment for General, Trauma and Reconstructive Surgery, Ludwig Maximilian University Munich, Marchioninstr. 15, 81377 Munich, GermanyBackground: Plain radiography (XR) series are standard of care for detection of fall-related fractures in older patients with low-energy falls (LEF) in the emergency department (ED). We have investigated the prevalence of fractures and diagnostic accuracy of XR imaging in the ED. Methods: 2839 patients with LEF, who were presented to two urban level I trauma centers in 2016 and received XR and computed tomography (CT), were consecutively included in this retrospective cohort study. The primary endpoint was the prevalence of fractures of the vertebral column, rib cage, pelvic ring, and proximal long bones. Secondary endpoints were diagnostic accuracy of XR for fracture detection with CT as reference standard and cumulative radiation doses applied. Results: Median age was 82 years (range 65−105) with 64.1% female patients. Results revealed that 585/2839 (20.6%) patients sustained fractures and 452/2839 (15.9%) patients received subsequent XR and CT examinations of single body regions. Cross-tabulation analysis revealed sensitivity of XR of 49.7%, a positive likelihood ratio of 27.6, and negative likelihood ratio of 0.5. Conclusions: XR is of moderate diagnostic accuracy for ruling-out fractures of the spine, pelvic ring, and rib cage in older patients with LEF. Prospective validations are required to investigate the overall risk−benefit of direct CT imaging strategies, considering the trade-off between diagnostic safety, health care costs, and radiation exposure.https://www.mdpi.com/2077-0383/9/1/97low-energy fallolder adultcomputed tomographyfracturex-ray
collection DOAJ
language English
format Article
sources DOAJ
author Alina Lampart
Isabelle Arnold
Nina Mäder
Sandra Niedermeier
Armin Escher
Robert Stahl
Christoph Trumm
Christian Kammerlander
Wolfgang Böcker
Christian H. Nickel
Roland Bingisser
Vera Pedersen
spellingShingle Alina Lampart
Isabelle Arnold
Nina Mäder
Sandra Niedermeier
Armin Escher
Robert Stahl
Christoph Trumm
Christian Kammerlander
Wolfgang Böcker
Christian H. Nickel
Roland Bingisser
Vera Pedersen
Prevalence of Fractures and Diagnostic Accuracy of Emergency X-ray in Older Adults Sustaining a Low-Energy Fall: A Retrospective Study
Journal of Clinical Medicine
low-energy fall
older adult
computed tomography
fracture
x-ray
author_facet Alina Lampart
Isabelle Arnold
Nina Mäder
Sandra Niedermeier
Armin Escher
Robert Stahl
Christoph Trumm
Christian Kammerlander
Wolfgang Böcker
Christian H. Nickel
Roland Bingisser
Vera Pedersen
author_sort Alina Lampart
title Prevalence of Fractures and Diagnostic Accuracy of Emergency X-ray in Older Adults Sustaining a Low-Energy Fall: A Retrospective Study
title_short Prevalence of Fractures and Diagnostic Accuracy of Emergency X-ray in Older Adults Sustaining a Low-Energy Fall: A Retrospective Study
title_full Prevalence of Fractures and Diagnostic Accuracy of Emergency X-ray in Older Adults Sustaining a Low-Energy Fall: A Retrospective Study
title_fullStr Prevalence of Fractures and Diagnostic Accuracy of Emergency X-ray in Older Adults Sustaining a Low-Energy Fall: A Retrospective Study
title_full_unstemmed Prevalence of Fractures and Diagnostic Accuracy of Emergency X-ray in Older Adults Sustaining a Low-Energy Fall: A Retrospective Study
title_sort prevalence of fractures and diagnostic accuracy of emergency x-ray in older adults sustaining a low-energy fall: a retrospective study
publisher MDPI AG
series Journal of Clinical Medicine
issn 2077-0383
publishDate 2019-12-01
description Background: Plain radiography (XR) series are standard of care for detection of fall-related fractures in older patients with low-energy falls (LEF) in the emergency department (ED). We have investigated the prevalence of fractures and diagnostic accuracy of XR imaging in the ED. Methods: 2839 patients with LEF, who were presented to two urban level I trauma centers in 2016 and received XR and computed tomography (CT), were consecutively included in this retrospective cohort study. The primary endpoint was the prevalence of fractures of the vertebral column, rib cage, pelvic ring, and proximal long bones. Secondary endpoints were diagnostic accuracy of XR for fracture detection with CT as reference standard and cumulative radiation doses applied. Results: Median age was 82 years (range 65−105) with 64.1% female patients. Results revealed that 585/2839 (20.6%) patients sustained fractures and 452/2839 (15.9%) patients received subsequent XR and CT examinations of single body regions. Cross-tabulation analysis revealed sensitivity of XR of 49.7%, a positive likelihood ratio of 27.6, and negative likelihood ratio of 0.5. Conclusions: XR is of moderate diagnostic accuracy for ruling-out fractures of the spine, pelvic ring, and rib cage in older patients with LEF. Prospective validations are required to investigate the overall risk−benefit of direct CT imaging strategies, considering the trade-off between diagnostic safety, health care costs, and radiation exposure.
topic low-energy fall
older adult
computed tomography
fracture
x-ray
url https://www.mdpi.com/2077-0383/9/1/97
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