Quantity and Quality of Inhaled Dose Predicts Immunopathology in Tuberculosis

Experimental animal models of tuberculosis (TB) have convincingly demonstrated that inhaled dose predicts immunopathology and survival. In contrast, the importance of inhaled dose has generally not been appreciated in TB epidemiology, clinical science, or the practice of TB control. Infectiousnes...

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Bibliographic Details
Main Authors: Kevin Patrick Fennelly, Edward C. Jones-Lopez
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00313/full