The New Salicylate Derivative UR-1505 Modulates the Th2/Humoral Response in a Dextran Sodium Sulphate Model of Colitis That Resembles Ulcerative Colitis

The New Salicylate Derivative UR-1505 Modulates the Th2/Humoral Response in a Dextran Sodium Sulphate Model of Colitis That Resembles Ulcerative Colitis

The aim of the present study was to evaluate the inmunomodulatory effects of UR-1505, a new salicylate derivative, on the T helper (Th)2 / humoral response produced during dextran sodium sulfate (DSS)-induced rat colitis. In the in vitro studies, UR-1505 (300 μM) inhibited both the production of int...

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Bibliographic Details
Main Authors:	Elvira Bailón, Juan Román, Isabel Ramis, Pedro Michelena, Dolors Balsa, Manuel Merlos, Antonio Zarzuelo, Julio Gálvez, Mònica Comalada
Format:	Article
Language:	English
Published:	Elsevier 2009-01-01
Series:	Journal of Pharmacological Sciences
Online Access:	http://www.sciencedirect.com/science/article/pii/S134786131934157X

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