Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

Amyloids result from the aggregation of a set of diverse proteins, due to either specific mutations or promoting intra- or extra-cellular conditions. Structurally, they are rich in intermolecular β-sheets and are the causative agents of several diseases, both neurodegenerative and systemic....

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Bibliographic Details
Main Authors: Sofia Giorgetti, Claudio Greco, Paolo Tortora, Francesco Antonio Aprile
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
amyloid diseases
biocomputing
drug design
natural antiamyloids
Online Access:http://www.mdpi.com/1422-0067/19/9/2677

Internet

http://www.mdpi.com/1422-0067/19/9/2677

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