Fraction from Wax Apple [<em>Syzygium samarangense</em> (Blume) Merrill and Perry] Fruit Extract Ameliorates Insulin Resistance via Modulating Insulin Signaling and Inflammation Pathway in Tumor Necrosis Factor α-Treated FL83B Mouse Hepatocytes

Fraction from Wax Apple [<em>Syzygium samarangense</em> (Blume) Merrill and Perry] Fruit Extract Ameliorates Insulin Resistance via Modulating Insulin Signaling and Inflammation Pathway in Tumor Necrosis Factor α-Treated FL83B Mouse Hepatocytes

Inflammation is associated with the development of insulin resistance in Type 2 diabetes mellitus. In the present study, mouse FL83B cells were treated with tumor necrosis factor-alpha (TNF-α) to induce insulin resistance, and then co-incubated with a fraction from wax apple fruit extract (FWFE). Th...

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Bibliographic Details
Main Authors: Szu-Chuan Shen, Wen-Chang Chang, Chiao-Li Chang
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:International Journal of Molecular Sciences
Subjects:
wax apple
insulin resistance
glucose uptake
western blot
inflammation
Online Access:http://www.mdpi.com/1422-0067/13/7/8562

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