Role of the miR-133a-5p/FBXO6 axis in the regulation of intervertebral disc degeneration

Role of the miR-133a-5p/FBXO6 axis in the regulation of intervertebral disc degeneration

Objective: Low back pain is a leading cause of disabilities worldwide, and intervertebral disc degeneration (IVDD)-related disorders have been recognised as one of the main contributors. Nevertheless, the underlying mechanism has not yet been fully understood. The aim of this study was to investigat...

Full description

Bibliographic Details
Main Authors: Xian-Fa Du, Hai-Tao Cui, He-Hai Pan, Jun Long, Hao-Wen Cui, Shun-Lun Chen, Jian-Ru Wang, Ze-Min Li, Hui Liu, Yong-Can Huang, Hua Wang, Zhao-Min Zheng
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Journal of Orthopaedic Translation
Subjects:
Intervertebral disc
miR-133a-5p
FBXO6
Nucleus pulposus cells
Interleukin (IL)-1β
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X21000401

Internet

http://www.sciencedirect.com/science/article/pii/S2214031X21000401

Similar Items