Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis

Summary: The cross-talk between mesenchymal stem and stromal cells (MSCs) and macrophages is critical for the restoration of tissue homeostasis after injury. Here, we demonstrate a pathway through which MSCs instruct macrophages to resolve inflammation and preserve tissue-specific stem cells, leadin...

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Bibliographic Details
Main Authors: Jung Hwa Ko, Hyeon Ji Kim, Hyun Jeong Jeong, Hyun Ju Lee, Joo Youn Oh
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720302308