The structure of cerebrosides in Gaucher's disease*

Crystalline cerebrosides were isolated from the spleen of a woman with Gaucher's disease. The cerebrosides accounted for 38 per cent of the total spleen lipids and 0.89 per cent of the fresh spleen. The sugar moiety of the cerebrosides was found to be glucose and its position of attachment was...

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Main Authors:	G.V. Marinetti, T. Ford, Elmer Stotz
Format:	Article
Language:	English
Published:	Elsevier 1960-04-01
Series:	Journal of Lipid Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520390635

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spelling	doaj-3bc123499b404d6581f4ce8f1118b4052021-04-23T06:11:02ZengElsevierJournal of Lipid Research0022-22751960-04-0113203207The structure of cerebrosides in Gaucher's disease*G.V. Marinetti0T. Ford1Elmer Stotz2Department of Biochemistry, University of Rochester School of Medicine and Dentistry, Rochester 20, N. Y.Department of Biochemistry, University of Rochester School of Medicine and Dentistry, Rochester 20, N. Y.Department of Biochemistry, University of Rochester School of Medicine and Dentistry, Rochester 20, N. Y.Crystalline cerebrosides were isolated from the spleen of a woman with Gaucher's disease. The cerebrosides accounted for 38 per cent of the total spleen lipids and 0.89 per cent of the fresh spleen. The sugar moiety of the cerebrosides was found to be glucose and its position of attachment was establihed to be on the primary hydroxyl group of sphingosine. The double bond in the sphingosine moiety had the trans configuration. The fatty acids of the cerebroside were determined by gas chromatography and paper chromatography and found to be mainly lignoceric, behenic, and palmitic acid. Small amounts of arachidic and stearic acids were also present.http://www.sciencedirect.com/science/article/pii/S0022227520390635
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	G.V. Marinetti T. Ford Elmer Stotz
spellingShingle	G.V. Marinetti T. Ford Elmer Stotz The structure of cerebrosides in Gaucher's disease* Journal of Lipid Research
author_facet	G.V. Marinetti T. Ford Elmer Stotz
author_sort	G.V. Marinetti
title	The structure of cerebrosides in Gaucher's disease*
title_short	The structure of cerebrosides in Gaucher's disease*
title_full	The structure of cerebrosides in Gaucher's disease*
title_fullStr	The structure of cerebrosides in Gaucher's disease*
title_full_unstemmed	The structure of cerebrosides in Gaucher's disease*
title_sort	structure of cerebrosides in gaucher's disease*
publisher	Elsevier
series	Journal of Lipid Research
issn	0022-2275
publishDate	1960-04-01
description	Crystalline cerebrosides were isolated from the spleen of a woman with Gaucher's disease. The cerebrosides accounted for 38 per cent of the total spleen lipids and 0.89 per cent of the fresh spleen. The sugar moiety of the cerebrosides was found to be glucose and its position of attachment was establihed to be on the primary hydroxyl group of sphingosine. The double bond in the sphingosine moiety had the trans configuration. The fatty acids of the cerebroside were determined by gas chromatography and paper chromatography and found to be mainly lignoceric, behenic, and palmitic acid. Small amounts of arachidic and stearic acids were also present.
url	http://www.sciencedirect.com/science/article/pii/S0022227520390635
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The structure of cerebrosides in Gaucher's disease*

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