Tumor suppressor lnc-CTSLP4 inhibits EMT and metastasis of gastric cancer by attenuating HNRNPAB-dependent Snail transcription

Tumor suppressor lnc-CTSLP4 inhibits EMT and metastasis of gastric cancer by attenuating HNRNPAB-dependent Snail transcription

Tumor metastasis is a crucial impediment to the treatment of gastric cancer (GC), and the epithelial-to-mesenchymal transition (EMT) program plays a critical role for the initiation of GC metastasis. Thus, the aim of this study is to investigate the regulation of lnc-CTSLP4 in the EMT process during...

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Bibliographic Details
Main Authors: Tao Pan, Zhenjia Yu, Zhijian Jin, Xiongyan Wu, Airong Wu, Junyi Hou, Xinyu Chang, Zhiyuan Fan, Jianfang Li, Beiqin Yu, Fangyuan Li, Chao Yan, Zhongyin Yang, Zhenggang Zhu, Bingya Liu, Liping Su
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
lnc-CTSLP4
Hsp90α
HNRNPAB
ZFP91
Snail;LncRNA
EMT
Online Access:http://www.sciencedirect.com/science/article/pii/S216225312100038X

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